Clinical studies have shown Arthrosamid® to have a strong safety profile, with no serious treatment related adverse events reported. The most commonly observed side effects included temporary joint discomfort or a feeling of swelling following the injection, which were generally mild and resolved within days to weeks.

The injectable hydrogel technology used in Arthrosamid® has also been utilized in medical applications for more than 20 years, supporting its established safety profile across various treatments.

A guided rehabilitation or physiotherapy program may help support your recovery and optimize results following Arthrosamid® treatment. Your clinician can help recommend an appropriate plan based on your symptoms, activity level, and goals. Additional rehabilitation resources are also available through the Arthrosamid® website.

Some patients may begin to notice pain relief within the first 24 hours following treatment. However, the full benefits of Arthrosamid® typically develop gradually over time, with maximum improvement often occurring between 4 to 12 weeks. Clinical studies show that many patients begin experiencing meaningful symptom improvement within the first few weeks after injection.

Following Arthrosamid® treatment, it is generally recommended to avoid strenuous or high impact activities — such as jogging, tennis, or long walks — for the first few weeks after the injection. Gradually returning to activity and beginning rehabilitation exercises, when appropriate, may help support recovery and optimize results. Your clinician can provide guidance based on your individual symptoms and activity goals.

Arthrosamid® is administered as a single injection directly into the knee joint. Before the procedure, a local anesthetic is used to help numb the area and improve comfort during treatment. In some cases, antibiotics may also be provided as a precaution to reduce the risk of infection.

The knee is carefully cleaned and prepared prior to the injection. Arthrosamid® is then injected into the synovial cavity of the knee, often using ultrasound guidance to ensure accurate placement. Once the procedure is complete, the needle is removed and a small dressing is applied over the injection site.

Patients in the under 70 years group reported close to 80% positive response rate following treatment with
Arthrosamid®.

Arthrosamid® is designed to provide long lasting symptom relief for knee osteoarthritis. The hydrogel used in the injection is non biodegradable, meaning it remains within the joint rather than being broken down over time.

Clinical studies have shown that many patients experience significant pain reduction within the first 4 weeks following treatment, with improvements in pain and function maintained for up to 5 years in follow up data. Individual results may vary depending on the severity of arthritis, activity level, and overall joint health.